Driving Innovation, Collaboration, and Patient-Centered Care
An inspiring week at TCT 2025 in San Francisco! We were honored to take part in the world’s leading interventional cardiology congress, presenting our research, exchanging ideas with global experts, and celebrating the innovation shaping the future of cardiovascular medicine. From groundbreaking studies to meaningful conversations, this year’s TCT highlighted the collective drive toward safer, smarter, and more compassionate patient care. A heartfelt thank you to our colleagues, partners, and friends who continue to push boundaries, share knowledge, and advance excellence in every aspect of our field. Together, we move forward — with purpose, passion, and a shared commitment to transforming cardiovascular care.
PICCOLETO X Study: Pioneering Stent-Free Revascularization in Chronic Total Occlusions (CTO)
We are extremely honored to announce that the PICCOLETO X study “Stent-Free Revascularization in CTO: Clinical Performance of Drug-Coated Balloons in De Novo and ISR CTO” will be presented at TCT 2025 – Transcatheter Cardiovascular Therapeutics, taking place October 25-28 in San Francisco. Selected as Best Global Research in Coronary Studies, this landmark multicenter real-world study provides robust evidence supporting the safety and efficacy of #drugcoatedballoons (DCB) and reduced-metal strategies in complex coronary interventions, marking a significant advancement in cardiovascular therapeutics. As the landscape of coronary intervention continues to evolve, the PICCOLETO X study provides critical insights that promote precision, safety, and enhanced patient care in CTO revascularization
Honoured to have our MUS.E I study makes TCTMD’s Top 10 Stories for October 2025
Our MUS.E I trial, showing the transformative power of tailored music therapy before and during PCI, is now officially one of TCTMD’s most popular cardiovascular stories of the month, ranking #4 among global cardiology breakthroughs presented at TCT 2025 in San Francisco, CA.
This recognition highlights how an innovative, human-centred, non-pharmacological approach can transform the patient experience: reducing post-procedural blood pressure, heart rate, and pain, all while being safe, affordable, and patient-centred.
Being featured alongside groundbreaking innovations in thrombectomy, valve interventions, and novel PCI technologiesunderscores the growing appreciation for holistic, human-centered care in cardiology.
Next up: MUS.E II and beyond! We’ll continue exploring how music—and immersive virtual reality—can reduce stress and enhance outcomes during PCI, pushing the boundaries of patient-centred innovation in cardiology. The future of PCI care may start with a playlist. 🎵
Study Chairman: Prof. Bernardo Cortese
Our team: Rima Chaddad, MD; Marco Frazzetto, MD; Beatrice Barbano, MT; Sara Malakouti, MD; Irfan Ullah, MD; Cataldo Strangi
📖 Dive into TCTMD’s full story
Delighted to have our 𝗠𝗨𝗦.𝗘 𝗜 study highlighted by 𝗧𝗖𝗧 2025