PICCOLETO IV–EPIC 38 officially underway – First Patient Enrolled

We are honored to announce the first patient enrollment by Dr. Davide Sala from Istituto Auxologico Italiano – Ospedale San Luca in PICCOLETO IV – EPIC 38, an investigator-driven, multi-national RCT led by Fondazione RIC with the collaboration of Fundacion EPIC.

We sincerely thank the team at Istituto Auxologico Italiano Ospedale San Luca for their outstanding dedication in making this significant progress possible

The trial will compare Single vs. Dual Antiplatelet Therapy (SAPT vs. DAPT) in high bleeding risk and elderly patients undergoing Drug-Coated Balloon (DCB) treatment, generating evidence to improve care for this vulnerable population.