
The launch of PICCOLETO IV-EPIC, now featured in Cardiovascular News, marks a new chapter in interventional cardiology. This international, investigator-driven trial evaluates whether single-antiplatelet therapy (SAPT) following PCI with latest-generation drug-coated balloons (DCBs) can provide a safer and effective alternative for elderly patients and those at high bleeding risk.
Led by Fondazione RIC, DCB Academy and Fundación EPIC, PICCOLETO IV-EPIC addresses a key unmet need in high-risk coronary populations by exploring SAPT as an alternative to standard dual antiplatelet therapy!!



Fondazione Ricerca e Innovazione Cardiovascolare and Fundación EPIC Launch PICCOLETO IV-EPIC Clinical Trial